School of Physics and Astrophysics

Postgraduate research profiles

Contact

Jonathon David Thompson

Phone: (+61 8) 6318 2845


Supervisors

Start date

Mar 2013

Submission date

Jan 2016

Jonathon David Thompson

Thesis

Commissioning of Dynamic Conformal Arc Therapy and Dosimetric Analysis in Stereotactic Ablative Radiotherapy

Summary

This study aims to commission a radiation treatment technique (DCAT) for use at Perth Radiation Oncology (Genesis Cancer Care WA) and evaluate it dosimetrically in comparison to other pre-existing treatment modalities when used in stereotactic ablative radiotherapy (SABR). There is also the potential for DCAT to be used clinically if it is determined to be a superior treatment delivery technique. The effect of couch and immobilisation devices on skin dose when DCAT is used for SABR will also be investigated as this has been shown to be significant in stereotactic treatments.

Why my research is important

Stereotactic radiotherapy has traditionally been confined to treatments of brain tumours but in recent years has been adapted for use in many sites around the body. It is becoming increasingly popular as a treatment option for many reasons, including the few treatments required (between 1-5 as compared to 30 or so for traditional radiotherapy) and the success rates seen so far. Due to the extremely high doses of radiation involved per treatment, it is imperative that the treatment is delivered as accurately as possible and that normal tissue around the tumour is spared as much as possible. Preliminary indications show that DCAT, whilst simpler than more recent techniques, may be a useful tool for achieving these goals. This research will compare DCAT against other modern SABR techniques such as VMAT (Volumetric Modulated Arc Therapy) and non-coplanar 3D CRT with the ultimate goal being to find the best treatment modality to use with SABR treatments at Perth Radiation Oncology.

The skin sparing effect that is seen in megavoltage beams is compromised when objects are placed between the patient and the beam – as is the case with the treatment couch and immobilisation devices. This isn’t such as issue in traditional radiotherapy as the doses involved are relatively low; however in SABR the doses delivered have the potential to cause serious injury to the patient’s skin if the effects of these devices are not considered. As such, this research will also characterise these effects when DCAT is used in SABR treatments and compare with other treatment modalities.

Funding

  • Genesis Cancer Care WA


 

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Last updated:
Monday, 2 August, 2010 2:54 PM

http://www.physics.uwa.edu.au/1023927